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Use it twice daily, morning and evening, for best results

In the ER, cholesterol accumulation disrupts calcium homeostasis and triggers ER stress, leading to -cell dysfunction and apoptosis

Diabetes Care 36 , 12721277 (2013)

The measurements in this study were taken from two voxels, positioned in two anatomically and functionally different parts of the ACC, its rostral portion, the pregenual ACC (pgACC) and in its dorsal portion, the dorsal ACC (dACC) [33]